5-ASA Drugs

Ulcerative colitis (UC), a form of inflammatory bowel disease that primarily affects the lining of the large intestine and rectum, presents a significant challenge in medical management due to its chronic nature and variable symptom profile. For many patients and clinicians, the journey to control the disease involves a strategic use of medications including corticosteroids and 5-aminosalicylic acid (5-ASA) drugs. This approach, while effective, requires a careful balance to manage flare-ups and maintain remission over the long term. Initial Attack: Corticosteroids to the Rescue During a flare-up, UC symptoms—which include severe diarrhea, rectal bleeding, abdominal pain, and fatigue—can be debilitating.…